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SA Instruments
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Image Search Results
Journal: Scientific Reports
Article Title: Expression and relevance of the G protein-gated K + channel in the mouse ventricle
doi: 10.1038/s41598-018-19719-x
Figure Lengend Snippet: HR analysis of constitutive and ventricle-specific Girk −/− mice. ( a , b ) Segments of ECG recordings from anesthetized wild-type ( a ) and Girk4 −/− ( b ) mice, at baseline and after injection of CCh (1.0 mg/kg i.p.). Scale: 1 s. ( c ) Summary of HR data at baseline and after injection of CCh for wild-type (n = 12) and Girk4 −/− (n = 13) mice. Two-way ANOVA analysis revealed an interaction between genotype and treatment (F 1,23 = 54.8, P < 0.001). Symbols: ** , *** P < 0.01 and 0.001, respectively, vs. baseline (within genotype); ## P < 0.01 vs. wild-type (within treatment). ( d ) Summary of HR data at baseline and after injection of CCh for MLC2VCre(+): Girk1 fl/fl (n = 13) and MLC2VCre(−): Girk1 fl/fl (n = 12) littermates. There was a significant main effect of treatment (F 1,23 = 173.1, P < 0.001), but no main effect of genotype (F 1,23 = 3.6, P = 0.070), or interaction between genotype and treatment (F 1,23 = 0.09, P = 0.77). Symbols: *** P < 0.001 vs. baseline (within genotype).
Article Snippet:
Techniques: Injection